apalutamide will decrease the level or outcome of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medicines that are CYP3A4 substrates can lead to lessen publicity to these prescription drugs.You might have moderate vagina… Read More